Linker-Region Modified Derivatives of the Deoxyhypusine Synthase Inhibitor CNI-1493 Suppress HIV-1 Replication-Reference-Cited by-同舟云学术

Linker-Region Modified Derivatives of the Deoxyhypusine Synthase Inhibitor CNI-1493 Suppress HIV-1 Replication

Published:2016-01-03 Issue:2 Volume:349 Page:91-103
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Schröder Marcus¹,Kolodzik Adrian²,Windshügel Björn²,Krepstakies Marcel³,Priyadarshini Poornima³,Hartjen Philip⁴,van Lunzen Jan⁴,Rarey Matthias²,Hauber Joachim³,Meier Chris¹

Affiliation:

1. Institute of Organic Chemistry, Department of Chemistry; Faculty of Sciences, University of Hamburg; Hamburg Germany

2. ZBH Center for Bioinformatics; University of Hamburg; Hamburg Germany

3. Heinrich Pette Institute - Leibniz Institute for Experimental Virology; Hamburg Germany

4. Department of Medicine, Infectious Diseases Unit; University Medical Center Hamburg-Eppendorf; Hamburg Germany

Funder

Bundesministerium für Bildung und Forschung

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201500323/fullpdf

Reference44 articles.

1. The Post-Translational Synthesis of a Polyamine-Derived Amino Acid, Hypusine, in the Eukaryotic Translation Initiation Factor 5A (eIF5A)

2. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification

3. Hypusine-containing protein eIF5A promotes translation elongation

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