Practical Synthesis of α-Amyrin, β-Amyrin, and Lupeol: The Potential Natural Inhibitors of Human Oxidosqualene Cyclase-Reference-Cited by-同舟云学术

Practical Synthesis of α-Amyrin, β-Amyrin, and Lupeol: The Potential Natural Inhibitors of Human Oxidosqualene Cyclase

Published:2017-10-13 Issue:12 Volume:350 Page:1700178
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Chen Dongyin¹²^ORCID,Xu Fengguo¹,Zhang Pu¹,Deng Jie¹,Sun Hongbin¹,Wen Xiaoan¹,Liu Jun¹

Affiliation:

1. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease and State Key Laboratory of Natural Medicines; China Pharmaceutical University; Nanjing China

2. Department of Medicinal Chemistry; School of Pharmacy; Nanjing Medical University; Nanjing China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Reference31 articles.

1. Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases

2. Antihyperglycemic and hypolipidemic effects of α, β-amyrin, a triterpenoid mixture from Protium heptaphyllum in mice

3. Protective effect of α- and β-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice

4. Protective effect of lupeol and its ester on cardiac abnormalities in experimental hypercholesterolemia

5. Protective effect of lupeol and lupeol linoleate in hypercholesterolemia associated renal damage

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