Synthesis of Some Novel 2,6-Disubstituted Pyridazin-3(2H )-one Derivatives as Analgesic, Anti-Inflammatory, and Non-Ulcerogenic Agents-Reference-Cited by-同舟云学术

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Synthesis of Some Novel 2,6-Disubstituted Pyridazin-3(2H )-one Derivatives as Analgesic, Anti-Inflammatory, and Non-Ulcerogenic Agents

Published:2017-08-09 Issue:9 Volume:350 Page:1700093
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Ibrahim Tamer H.¹,Loksha Yasser M.¹^ORCID,Elshihawy Hosam A.²,Khodeer Dina M.³,Said Mohamed M.²

Affiliation:

1. Department of Pharmaceutical Chemistry; Faculty of Pharmacy and Pharmaceutical Industries; Sinai University; Al-Arish North Sinai Egypt

2. Department of Pharmaceutical Organic Chemistry; Faculty of Pharmacy; Suez Canal University; Ismailia Egypt

3. Department of Pharmacology and Toxicology; Faculty of Pharmacy; Suez Canal University; Ismailia Egypt

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Reference29 articles.

1. Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond

2. Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

3. Cyclooxygenases: structural and functional insights

4. Design, synthesis, and evaluation of anti-inflammatory and ulcerogenicity of novel pyridazinone derivatives

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2. Pyridazine and pyridazinone derivatives: Synthesis and in vitro investigation of their anti‐inflammatory potential in LPS‐induced RAW264.7 macrophages;Drug Development Research;2024-03-21

3. New pyrazole–pyridazine hybrids as selective COX-2 inhibitors: design, synthesis, molecular docking, in silico studies and investigation of their anti-inflammatory potential by evaluation of TNF-α, IL-6, PGE-2 and NO in LPS-induced RAW264.7 macrophages;RSC Medicinal Chemistry;2024

4. 2-[4-(2-Chlorobenzyl)-3-methyl-6-oxo-1,6-dihydropyridazin-1-yl]-N-(4-fluorophenyl)acetamide;IUCrData;2023-10-19

5. One‐Pot Synthesis of Polycyclic 4,5‐Dihydropyridazine‐3(2H)‐ones by Inverse Electron‐Demand Diels–Alder (IEDDA) Reactions from Alkenes;Chemistry – A European Journal;2023-09-28

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