N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as β-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation

Author:

Edraki Najmeh1,Firuzi Omidreza1,Fatahi Yousef2,Mahdavi Mohammad2,Asadi Mehdi2,Emami Saeed3,Divsalar Kouros4,Miri Ramin1,Iraji Aida1,Khoshneviszadeh Mehdi1,Firoozpour Loghman5,Shafiee Abbas2,Foroumadi Alireza24

Affiliation:

1. Medicinal and Natural Products Chemistry Research Center; Shiraz University of Medical Sciences; Shiraz Iran

2. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center; Tehran University of Medical Sciences; Tehran Iran

3. Department of Medicinal Chemistry and Pharmaceutical Sciences Research Center, Faculty of Pharmacy; Mazandaran University of Medical Sciences; Sari Iran

4. Neuroscience Research Center, Institute of Neuropharmacology; Kerman University of Medicinal Sciences; Kerman Iran

5. Drug Design and Development Research Center; Tehran University of Medical Sciences; Tehran Iran

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

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