Feasibility of an online consensus approach for the diagnosis of cognitive impairment and dementia in rural South Africa

Author:

Bassil Darina T.1,Farrell Meagan T.1,Weerman Albert2,Guo Muqi1,Wagner Ryan G.3,Brickman Adam M.456,Glymour M. Maria7,Langa Kenneth M.891011,Manly Jennifer J.456,Tipping Brent12,Butler India12,Tollman Stephen3,Berkman Lisa F.113

Affiliation:

1. Harvard Center for Population and Development Studies Harvard University Cambridge Massachusetts USA

2. Center for Economic and Social Research University of Southern California Los Angeles California USA

3. MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt) School of Public Health Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa

4. Taub Institute for Research on Alzheimer's Disease and the Aging Brain Vagelos College of Physicians and Surgeons Columbia University New York New York USA

5. Gertrude H. Sergievsky Center Vagelos College of Physicians and Surgeons Columbia University New York New York USA

6. Department of Neurology Vagelos College of Physicians and Surgeons Columbia University New York New York USA

7. Department of Epidemiology and Biostatistics University of California San Francisco California USA

8. Institute for Healthcare Policy and Innovation University of Michigan Ann Arbor Michigan USA

9. Department of Internal Medicine University of Michigan Medical School Ann Arbor Michigan USA

10. Institute for Social Research University of Michigan Ann Arbor Michigan USA

11. Veterans Affairs Center for Clinical Management Research Ann Arbor Michigan USA

12. Division of Geriatric Medicine School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa

13. Department of Social and Behavioral Sciences Harvard T.H. Chan School of Public Health Boston Massachusetts USA

Abstract

AbstractINTRODUCTIONWe describe the development and feasibility of using an online consensus approach for diagnosing cognitive impairment and dementia in rural South Africa.METHODSCognitive assessments, clinical evaluations, and informant interviews from Cognition and Dementia in the Health and Aging in Africa Longitudinal Study (HAALSI Dementia) were reviewed by an expert panel using a web‐based platform to assign a diagnosis of cognitively normal, mild cognitive impairment (MCI), or dementia.RESULTSSix hundred thirty‐five participants were assigned a final diagnostic category, with 298 requiring adjudication conference calls. Overall agreement between each rater's independent diagnosis and final diagnosis (via the portal or consensus conference) was 78.3%. A moderate level of agreement between raters’ individual ratings and the final diagnostic outcomes was observed (average κ coefficient = 0.50).DISCUSSIONFindings show initial feasibility in using an online consensus approach for the diagnosis of cognitive impairment and dementia in remote, rural, and low‐resource settings.

Funder

National Institute on Aging

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

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