Recurrence and variability of germline EPCAM deletions in Lynch syndrome

Author:

Kuiper Roland P.1,Vissers Lisenka E.L.M.1,Venkatachalam Ramprasath1,Bodmer Danielle1,Hoenselaar Eveline1,Goossens Monique2,Haufe Aline3,Kamping Eveline1,Niessen Renée C.4,Hogervorst Frans B.L.5,Gille Johan J.P.6,Redeker Bert7,Tops Carli M.J.8,van Gijn Marielle E.9,van den Ouweland Ans M.W.10,Rahner Nils11,Steinke Verena11,Kahl Philip12,Holinski‐Feder Elke13,Morak Monika1314,Kloor Matthias15,Stemmler Susanne16,Betz Beate17,Hutter Pierre18,Bunyan David J.19,Syngal Sapna20,Culver Julie O.21,Graham Tracy22,Chan Tsun L.23,Nagtegaal Iris D.2,van Krieken J. Han J.M2,Schackert Hans K.3,Hoogerbrugge Nicoline1,van Kessel Ad Geurts1,Ligtenberg Marjolijn J.L.12

Affiliation:

1. Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

2. Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

3. Department of Surgical Research, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Germany

4. Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

5. Family Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, The Netherlands

6. Department of Clinical Genetics, VU Medical Center, Amsterdam, The Netherlands

7. Department of Human Genetics, Academic Medical Center, Amsterdam, The Netherlands

8. Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands

9. Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands

10. Department of Clinical Genetics, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands

11. Institute of Human Genetics, University of Bonn, Germany

12. Institute of Pathology, University of Bonn, Germany

13. University Hospital of the Ludwig‐Maximilians‐University, Campus Innenstadt, Munich, Germany

14. Center of Medical Genetics, Munich, Germany

15. Institute of Pathology, Department of Applied Tumor Biology, University Hospital Heidelberg, Heidelberg, Germany

16. Department of Human Genetics, Ruhr‐University Bochum, Germany

17. Institute of Human Genetics, Heinrich‐Heine‐University, Duesseldorf, Germany

18. Unit of Genetics, Institut Central des Hôpitaux Valaisans, Sion, Switzerland

19. Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, Wiltshire, United Kingdom

20. Department of Internal Medicine, Brigham and Women's Hospital, Boston, Massachusetts

21. Department of Clinical Cancer Genetics, City of Hope, Duarte, California

22. Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada

23. Hereditary Gastrointestinal Cancer Genetic Diagnosis Laboratory, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong

Funder

The Dutch Cancer Society

The Netherlands Organization for Health Research and Development

The Sacha Swarttouw-Hijmans Foundation

The Deutsche Krebshilfe

Publisher

Wiley

Subject

Genetics (clinical),Genetics

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