Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications
Author:
Publisher
Wiley
Subject
Neurology (clinical),Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/mds.23737/fullpdf
Reference71 articles.
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2. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology;Zimprich;Neuron.,2004
3. The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity;Gloeckner;Hum Mol Genet.,2006
4. The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity;Guo;Exp Cell Res.,2007
5. GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease;Ito;Biochemistry.,2007
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