CRISPR‐Net: A Recurrent Convolutional Network Quantifies CRISPR Off‐Target Activities with Mismatches and Indels-Reference-Cited by-同舟云学术

CRISPR‐Net: A Recurrent Convolutional Network Quantifies CRISPR Off‐Target Activities with Mismatches and Indels

Published:2020-05-20 Issue:13 Volume:7 Page:1903562
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Adv. Sci.

Author:

Lin Jiecong¹^ORCID,Zhang Zhaolei²³⁴,Zhang Shixiong¹,Chen Junyi¹,Wong Ka‐Chun¹^ORCID

Affiliation:

1. Department of Computer ScienceUniversity of Hong Kong Hong Kong

2. The Donnelly Centre for Cellular and Biomolecular ResearchUniversity of Toronto Toronto M5S 3E1 Canada

3. Department of Molecular GeneticsUniversity of Toronto Toronto M5S 3E1 Canada

4. Department of Computer ScienceUniversity of Toronto Toronto M5S 3E1 Canada

Funder

Health and Medical Research Fund

City University of Hong Kong

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.201903562

Reference51 articles.

1. Multiplex Genome Engineering Using CRISPR/Cas Systems

2. CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing

3. Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

4. The new frontier of genome engineering with CRISPR-Cas9

Cited by 50 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Learning to quantify uncertainty in off-target activity for CRISPR guide RNAs;Nucleic Acids Research;2024-09-14

2. Overcoming CRISPR-Cas9 off-target prediction hurdles: A novel approach with ESB rebalancing strategy and CRISPR-MCA model;PLOS Computational Biology;2024-09-03

3. A systematic method for solving data imbalance in CRISPR off-target prediction tasks;Computers in Biology and Medicine;2024-08

4. Generating, modeling and evaluating a large-scale set of CRISPR/Cas9 off-target sites with bulges;Nucleic Acids Research;2024-05-30

5. Artificial Intelligence and Computational Biology in Gene Therapy: A Review;Biochemical Genetics;2024-04-18