DNA‐Mediated Assembly of Multispecific Antibodies for T Cell Engaging and Tumor Killing-Reference-Cited by-同舟云学术

DNA‐Mediated Assembly of Multispecific Antibodies for T Cell Engaging and Tumor Killing

Published:2019-11-23 Issue:2 Volume:7 Page:1900973
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Adv. Sci.

Author:

Pan Liqiang¹,Cao Chan²,Run Changqing²,Zhou Liujuan²,Chou James J.³^ORCID

Affiliation:

1. Institute of Drug Metabolism and Pharmaceutical Analysis and Zhejiang Province Key Laboratory of Anti‐cancer Drug ResearchCollege of Pharmaceutical SciencesZhejiang University 310058 Hangzhou China

2. Assembly Medicine, LLC Shanghai 201203 China

3. Department of Biological Chemistry and Molecular PharmacologyHarvard Medical School Boston MA 02115 USA

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.201900973

Reference32 articles.

1. The making of bispecific antibodies

2. Bispecific antibodies: a mechanistic review of the pipeline

3. Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu.

4. A phase II study of the bispecific antibody MDX-H210 (anti-HER2 × CD64) with GM-CSF in HER2+ advanced prostate cancer

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