A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice-Reference-Cited by-同舟云学术

A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice

Published:2020-05-28 Issue:13 Volume:7 Page:1903451
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Adv. Sci.

Author:

Zhuo Zhenjian¹²,Wan Youyang³⁴,Guan Daogang³⁴⁵,Ni Shuaijian³⁴⁶,Wang Luyao³⁴⁶,Zhang Zongkang¹,Liu Jin³⁴,Liang Chao³⁴,Yu Yuanyuan³⁴⁶,Lu Aiping³⁴⁶,Zhang Ge³⁴^ORCID,Zhang Bao‐Ting¹

Affiliation:

1. School of Chinese MedicineFaculty of MedicineThe Chinese University of Hong Kong Hong Kong SAR China

2. Aptacure Therapeutics Limited Kowloon Hong Kong SAR China

3. Law Sau Fai Institute for Advancing Translational Medicine in Bone & Joint DiseasesSchool of Chinese MedicineHong Kong Baptist University Hong Kong SAR China

4. Institute of Integrated Bioinformedicine and Translational ScienceSchool of Chinese MedicineHong Kong Baptist University Hong Kong SAR China

5. Department of Biochemistry and Molecular BiologySchool of Basic Medical SciencesSouthern Medical UniversityGuangdong Provincial Key Laboratory of Single Cell Technology and Application Guangzhou 510515 China

6. Guangdong‐Hong Kong‐Macao Greater BayArea International Research Platform for Aptamer‐based Translational Medicine and Drug Discovery Hong Kong 999077 China

Funder

National Key R&D Program of China

National Natural Science Foundation Council of China

Interdisciplinary Research Clusters Matching Scheme of Hong Kong Baptist University

Hong Kong General Research Fund

Hong Kong Baptist University Strategic Development Fund

Science and Technology Innovation Commission of Shenzhen Municipality Funds

The Chinese University of Hong Kong

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.201903451

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