Cytochrome P450 2C9-natural antiarthritic interactions: Evaluation of inhibition magnitude and prediction from in vitro data

Author:

Tan Boon Hooi1,Ahemad Nafees2,Pan Yan3,Palanisamy Uma Devi4ORCID,Othman Iekhsan4,Yiap Beow Chin5,Ong Chin Eng5ORCID

Affiliation:

1. Division of Applied Biomedical Sciences and Biotechnology; International Medical University; Bukit Jalil Kuala Lumpur Malaysia

2. School of Pharmacy; Monash University Malaysia; Bandar Sunway Selangor Malaysia

3. Department of Biomedical Science; University of Nottingham Malaysia Campus; Semenyih Selangor Malaysia

4. Jeffrey Cheah School of Medicine and Health Sciences; Monash University Malaysia; Bandar Sunway Selangor Malaysia

5. School of Pharmacy; International Medical University; Bukit Jalil Kuala Lumpur Malaysia

Funder

Kementerian Sains, Teknologi dan Inovasi

Monash University Malaysia Seed Grant

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference38 articles.

1. Inhibition constants, inhibitor concentrations and the prediction of inhibitory drug drug interactions: pitfalls, progress and promise;Bachmann;Current Drug Metabolism,2006

2. Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9;Boye;Xenobiotica,2004

3. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding;Bradford;Analytical Biochemistry,1976

4. Prediction of in vivo drug-drug interactions from in vitro data: factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4;Brown;Clinical Pharmacokinetics,2006

5. A randomized, double blind, placebo controlled trial of a topical cream containing glucosamine sulfate, chondroitin sulfate, and camphor for osteoarthritis of the knee;Cohen;The Journal of Rheumatology,2003

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