Advanced multivariate data analysis to determine the root cause of trisulfide bond formation in a novel antibody-peptide fusion-Reference-Cited by-同舟云学术

Advanced multivariate data analysis to determine the root cause of trisulfide bond formation in a novel antibody-peptide fusion

Published:2017-06-05 Issue:10 Volume:114 Page:2222-2234
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Goldrick Stephen¹²^ORCID,Holmes William²,Bond Nicholas J.²,Lewis Gareth²,Kuiper Marcel²,Turner Richard²,Farid Suzanne S.¹

Affiliation:

1. Department of Biochemical Engineering, The Advanced Centre of Biochemical Engineering; University College London; Gordon Street WC1H 0AH London United Kingdom

2. MedImmune; Granta Park; Cambridge CB21 6GH United Kingdom

Funder

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bit.26339/fullpdf

Reference56 articles.

1. A review of advanced small-scale parallel bioreactor technology for accelerated process development: Current state and future need;Bareither;Biotechnol Prog,2011

2. Characterization of therapeutic antibodies and related products;Beck;Anal Chem,2012

3. Becker P Christensen T. 2006

4. Statistical media optimization and alkaline protease production from Bacillus mojavensis in a bioreactor;Beg;Process Biochem,2003

5. Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells;Borys;Biotechnology,1993

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Predictive modeling for cell culture in commercial manufacturing of biotherapeutics;Biotechnology and Bioengineering;2024-07-18

2. Robust method for chromatogram shape analysis to improve early detection of performance drifts and adverse changes in process parameters during purification column operations;Biotechnology Journal;2023-12-11

3. Enhanced harvest performance predictability through advanced multivariate data analysis of mammalian cell culture particle size distribution;Biotechnology and Bioengineering;2023-11-02

4. Impact of Trisulfide on the Structure and Function of Different Antibody Constructs;Journal of Pharmaceutical Sciences;2023-10

5. Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics;Frontiers in Bioengineering and Biotechnology;2023-06-05