1. Department of Biomathematics, David Geffen School of Medicine at UCLA Los Angeles CA 90095 USA
2. Janssen Research and Development LLC Titusville NJ 08869 USA
3. Department of Statistics Columbia University New York NY 10027 USA
4. Department of Biostatistics, UCLA Fielding School of Public Health Los Angeles CA 90024 USA
5. Department of Human Genetics, David Geffen School of Medicine at UCLA Los Angeles CA 90095 USA