The Application of CRISPR/Cas Technology to Efficiently Model Complex Cancer Genomes in Stem Cells

Author:

Albitar Adam1,Rohani Bahar1,Will Brett1,Yan Annie1,Gallicano G. Ian1ORCID

Affiliation:

1. Biochemistry and Cellular & Molecular BiologyGeorgetown University Medical CenterWashington20007District of Columbia

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference34 articles.

1. ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

2. Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

3. MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia

4. CollinsFS.2015. Statement on NIH funding of research using gene‐editing technologies in human embryos. 2017.https://www.nih.gov/about‐nih/who‐we‐are/nih‐director/statements/statement‐nih‐funding‐research‐using‐gene‐editing‐technologies‐human‐embryos

5. CyranoskiD.2016. Chinese scientists to pioneer first human CRISPR trial: Nature News & Comment 2017.

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