Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [ <sup>11</sup> C]UCB‐J-Reference-Cited by-同舟云学术

Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [ ¹¹ C]UCB‐J

Published:2022-02-17 Issue:12 Volume:18 Page:2527-2536
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Mecca Adam P.¹²,O'Dell Ryan S.¹²,Sharp Emily S.¹³,Banks Emmie R.¹²,Bartlett Hugh H.¹²,Zhao Wenzhen¹²,Lipior Sylwia¹²,Diepenbrock Nina G.¹²,Chen Ming‐Kai⁴,Naganawa Mika⁴,Toyonaga Takuya⁴,Nabulsi Nabeel B.⁴,Vander Wyk Brent C.⁵,Arnsten Amy F. T.¹⁶,Huang Yiyun⁵,Carson Richard E.⁵,van Dyck Christopher H.¹²³⁶

Affiliation:

1. Alzheimer's Disease Research Unit Yale University School of Medicine New Haven Connecticut USA

2. Department of Psychiatry Yale University School of Medicine New Haven Connecticut USA

3. Department of Neurology Yale University School of Medicine New Haven Connecticut USA

4. Department of Radiology and Biomedical Imaging Yale University School of Medicine New Haven Connecticut USA

5. Program on Aging Yale University School of Medicine New Haven Connecticut USA

6. Department of Neuroscience Yale University School of Medicine New Haven Connecticut USA

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12582

Reference28 articles.

1. Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

2. Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

3. Three-Dimensional Analysis of the Relationship Between Synaptic Pathology and Neuropil Threads in Alzheimer Disease

4. Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment

5. Brain contains two forms of synaptic vesicle protein 2.

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