Repeated dosing of piperine induced gene expression of P-glycoprotein via stimulated pregnane-X-receptor activity and altered pharmacokinetics of diltiazem in rats-Reference-Cited by-同舟云学术

Repeated dosing of piperine induced gene expression of P-glycoprotein via stimulated pregnane-X-receptor activity and altered pharmacokinetics of diltiazem in rats

Published:2012-09-18 Issue:8 Volume:33 Page:446-454
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Qiang Fu¹,Kang Keon-Wook²,Han Hyo-Kyung¹

Affiliation:

1. College of Pharmacy; Dongguk University; Pil-dong-3-ga, Jung-gu; Seoul; Korea

2. College of Pharmacy; Seoul National University; 1 Gwanak-ro, Gwanak-gu; Seoul; Korea

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference36 articles.

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2. Diltiazem: ten years of clinical experience in the treatment of hypertension;Weir;J Clin Pharmacol,1995

3. Pharmacokinetics and metabolism of diltiazem in healthy males and females following a single oral dose;Yeung;Eur J Drug Metab Pharmacokinet,1993

4. Species comparison of pharmacokinetics and metabolism of diltiazem in humans, dogs, rabbits, and rats;Yeung;Drug Metab Dispos,1990

5. P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations;Cascorbi;Handb Exp Pharmacol,2011

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