Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities

Author:

Goeppert Benjamin1,Folseraas Trine23456,Roessler Stephanie1,Kloor Matthias7,Volckmar Anna‐Lena1,Endris Volker1,Buchhalter Ivo18,Stenzinger Albrecht1,Grzyb Krzysztof9,Grimsrud Marit M.234,Gornicka Barbara10,Seth Erik11,Reynolds Gary M.12,Franke Andre13,Gotthardt Daniel N.14,Mehrabi Arianeb15,Cheung Angela16,Verheij Joanne17,Arola Johanna18,Mäkisalo Heikki19,Eide Tor J.9,Weidemann Sören20,Cheville John C.21,Mazza Giuseppe22,Hirschfield Gideon M.1223,Ponsioen Cyriel Y.24,Bergquist Annika11,Milkiewicz Piotr2526,Lazaridis Konstantinos N.16,Schramm Christoph2728,Manns Michael P.29,Färkkilä Martti30,Vogel Arndt29,Boberg Kirsten M.23456,Schirmacher Peter1,Karlsen Tom H.23456,

Affiliation:

1. Department of General Pathology, Institute of Pathology University Hospital Heidelberg Heidelberg Germany

2. Norwegian PSC Research Center Department of Transplantation Medicine Division of Surgery, Inflammatory Medicine and Transplantation Oslo University Hospital Rikshospitalet Oslo Norway

3. Institute of Clinical Medicine Faculty of Medicine University of Oslo Oslo Norway

4. Research Institute of Internal Medicine Division of Surgery, Inflammatory Medicine and Transplantation Oslo University Hospital Rikshospitalet Oslo Norway

5. K.G. Jebsen Inflammation Research Center Institute of Clinical Medicine Faculty of Medicine University of Oslo Oslo Norway

6. Section for Gastroenterology Department of Transplantation Medicine Division of Surgery, Inflammatory Medicine and Transplantation Oslo University Hospital Rikshospitalet Oslo Norway

7. Department of Applied Tumor Biology Institute of Pathology University of Heidelberg Heidelberg Germany

8. Institute of Pathology, Omics IT and Data Management Core Facility, German Cancer Research Center (DKFZ) Heidelberg Germany

9. Department of Pathology Oslo University Hospital Oslo Norway

10. Department of Pathology Medical University of Warsaw Warsaw Poland

11. Department of Gastroenterology and Hepatology Karolinska Institutet Karolinska University Hospital Stockholm Sweden

12. Center for Liver Research NIHR Birmingham Liver Biomedical Research Unit University of Birmingham Birmingham United Kingdom

13. Institute of Clinical Molecular Biology Christian‐Albrechts University Kiel Germany

14. Department of Internal Medicine IV University Hospital Heidelberg Heidelberg Germany

15. Department of General, Visceral and Transplantation Surgery University of Heidelberg Heidelberg Germany

16. Division of Gastroenterology and Hepatology Mayo Clinic Rochester MN

17. Department of Pathology Academic Medical Center Amsterdam the Netherlands

18. Department of Pathology Haartman Institute and Huslab Helsinki University Hospital Helsinki Finland

19. Department of Transplantation and Liver Surgery Helsinki University Hospital Helsinki Finland

20. Institute of Pathology University Medical Center Hamburg‐Eppendorf Hamburg Germany

21. Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN

22. Division of Medicine Institute for Liver and Digestive Health Royal Free Hospital University College London London United Kingdom

23. University Hospital Birmingham NHS Foundation Trust Birmingham United Kingdom

24. Department of Gastroenterology and Hepatology Academic Medical Center Amsterdam the Netherlands

25. Liver and Internal Medicine Unit Medical University of Warsaw Warsaw Poland

26. Translational Medicine Group Pomeranian Medical University Szczecin Poland

27. Department of Medicine University Medical Center Hamburg‐Eppendorf Hamburg Germany

28. Martin Zeitz Center for Rare Diseases University Medical Center Hamburg‐Eppendorf Hamburg Germany

29. Department of Gastroenterology, Hepatology and Endocrinology Hannover Medical School Hannover Germany

30. Department of Gastroenterology & Hepatology Helsinki University Hospital Helsinki Finland

Publisher

Wiley

Subject

Hepatology

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