Gold nanoparticles-conjugated quercetin induces apoptosis via inhibition of EGFR/PI3K/Akt-mediated pathway in breast cancer cell lines (MCF-7 and MDA-MB-231)

Author:

Balakrishnan Solaimuthu1ORCID,Mukherjee Sudip23,Das Sourav23,Bhat Firdous Ahmad1,Raja Singh Paulraj1,Patra Chitta Ranjan23,Arunakaran Jagadeesan1ORCID

Affiliation:

1. Department of Endocrinology; Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras; Chennai Tamil Nadu India

2. Chemical Biology, CSIR-Indian Institute of Chemical Technology; Hyderabad Telangana State India

3. Academy of Scientific and Innovative Research (AcSIR); Training and Development Complex; Chennai India

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,General Medicine,Biochemistry

Reference66 articles.

1. American Cancer Society Cancer facts & figures 2016

2. Synthesis and characterisation of morin reduced gold nanoparticles and its cytotoxicity in MCF-7 cells;Kondath;Chem Biol Interact,2014

3. Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer;Mitsudomi;FEBS J,2010

4. Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress;Huang;BMC Cancer,2014

5. Synthesis and bio-functionalization of magnetic nanoparticles for medical diagnosis and treatment;Schladt;Dalton Trans,2011

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