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Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity

  • Published:2017-11-08 Issue:6 Volume:66 Page:2083-2085
  • ISSN:0270-9139
  • Container-title:Hepatology
  • language:en
  • Short-container-title:Hepatology

Author:

Ward E. Sally12,Ober Raimund J.13

Affiliation:

1. Department of Molecular and Cellular Medicine; Texas A&M University Health Science Center; College Station TX

2. Department of Microbial Pathogenesis and Immunology; Texas A&M University Health Science Center; Bryan TX

3. Department of Biomedical Engineering; Texas A&M University; College Station TX

Publisher

Wiley

Subject

Hepatology

Reference10 articles.

1. Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury;Pyzik;Proc Natl Acad Sci USA,2017

2. FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions;Curr Top Microbiol Immunol,2014

3. The immunologic functions of the neonatal Fc receptor for IgG;Rath;J Clin Immunol,2013

4. Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fc-γ receptor;Claypool;Mol Biol Cell,2004

5. Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level;Ober;Proc Natl Acad Sci USA,2004
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