Measurement of glycine in healthy and tumorous brain by triple-refocusing MRS at 3 T in vivo

Author:

Tiwari Vivek1,An Zhongxu1,Ganji Sandeep K.1,Baxter Jeannie1,Patel Toral R.23,Pan Edward234,Mickey Bruce E.345,Maher Elizabeth A.2456,Pinho Marco C.17,Choi Changho147ORCID

Affiliation:

1. Advanced Imaging Research Center; University of Texas Southwestern Medical Center; Dallas TX USA

2. Department of Neurology and Neurotherapeutics; University of Texas Southwestern Medical Center; Dallas TX USA

3. Department of Neurological Surgery; University of Texas Southwestern Medical Center; Dallas TX USA

4. Harold C. Simmons Cancer Center; University of Texas Southwestern Medical Center; Dallas TX USA

5. Annette Strauss Center for Neuro-Oncology; University of Texas Southwestern Medical Center; Dallas TX USA

6. Department of Internal Medicine; University of Texas Southwestern Medical Center; Dallas Texas USA

7. Department of Radiology; University of Texas Southwestern Medical Center; Dallas TX USA

Funder

National Cancer Institute

Cancer Prevention and Research Institute of Texas

Publisher

Wiley

Subject

Spectroscopy,Radiology Nuclear Medicine and imaging,Molecular Medicine

Reference46 articles.

1. The glycinergic inhibitory synapse;Legendre;Cell Mol Life Sci,2001

2. Glycine transporters: essential regulators of neurotransmission;Eulenburg;Trends Biochem Sci,2005

3. Glutamate and schizophrenia: phencyclidine, N-methyl-d-aspartate receptors, and dopamine-glutamate interactions;Javitt;Int Rev Neurobiol,2007

4. Measurement of glycine in a brain and brain tumors by means of 1H MRS;Bobek-Billewicz;Folia Neuropathol,2010

5. Studies of the glycine cleavage enzyme system in brain from infants with glycine encephalopathy;Perry;Pediatr Res,1977

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