Affiliation:
1. Department of Radiology The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine) Hangzhou Zhejiang China
2. The First School of Clinical Medicine of Zhejiang Chinese Medical University Hangzhou Zhejiang China
3. Medical Imaging Research Institute of Longgang, The Third People's Hospital of Longgang District Shenzhen Guangdong China
4. Department of Radiology Shenzhen Second People's Hospital Shenzhen Guangdong China
5. Zhouxin Medical Imaging and Health Screening Center Xiamen Fujian China
6. Department of Radiology and Nuclear Medicine, Xuanwu Hospital Capital Medical University Beijing China
7. Keck School of Medicine University of Southern California Los Angeles California USA
Abstract
BackgroundAlthough right atrial (RA) myocardial deformation has important implications for patient diagnosis, prognosis, and risk stratification, its implementation in clinical practice has been hampered by limited normal reference values, especially in Asian populations.PurposeTo establish age‐ and sex‐specific reference values for RA strain, strain rate (SR), and displacement based on a large sample of healthy Chinese adults using MR‐feature tracking (MR‐FT).Study TypeRetrospective.Population524 healthy Chinese adults (287 male; mean age 43.7 ± 11.9 years).Field Strength/Sequence1.5T/balanced steady‐state free precession.AssessmentRA deformation parameters, including reservoir, conduit, and booster strain (εs, εe, and εa), peak positive, early negative, and late negative SR (SRs, SRe, and SRa), and total, passive, and active displacement (Ds, De, and Da), were assessed using MR‐FT.Statistical TestsStudent's t‐test, one‐way ANOVA, coefficients of determination (r2), intraclass correlation coefficients (ICC), and Bland–Altman plots. A P value <0.05 was considered significant.ResultsWomen demonstrated significantly greater magnitudes of RA deformation parameters than men: εs (57.4% ± 15.1% vs. 44.3% ± 12.6%), εe (37.5% ± 13.4% vs. 27.4% ± 10.9%), εa (19.9% ± 5.7% vs. 16.9% ± 5.0%), SRs (2.62 ± 0.88 sec−1 vs. 2.00 ± 0.63 sec−1), SRe (−2.98 ± 1.26 sec−1 vs. −2.16 ± 0.92 sec−1), SRa (−2.28 ± 0.75 sec−1 vs. −1.84 ± 0.62 sec−1), Ds (−7.80 ± 1.90 mm vs. −7.46 ± 1.70 mm), and De (−4.84 ± 1.31 mm vs. −4.49 ± 1.21 mm). For both sexes, aging was significantly associated with decreased RA reservoir and conduit function (εs, SRs, Ds, εe, SRe, and De), and with increased εa and Da. RA deformation measurements had good to excellent intraobserver and interobserver reproducibility, with ICCs ranging from to 0.790 to 0.972.Data ConclusionThis study provides age‐ and sex‐specific reference values of RA strain, SR, and displacement based on a large cohort of healthy Chinese adults using MR‐FT.Level of Evidence3Technical EfficacyStage 2
Funder
National Natural Science Foundation of China
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献