Calibration and Validation of a Mechanistic COVID‐19 Model for Translational Quantitative Systems Pharmacology – A Proof‐of‐Concept Model Development for Remdesivir-Reference-Cited by-同舟云学术

Calibration and Validation of a Mechanistic COVID‐19 Model for Translational Quantitative Systems Pharmacology – A Proof‐of‐Concept Model Development for Remdesivir

Published:2022-06-29 Issue:4 Volume:112 Page:882-891
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Samieegohar Mohammadreza¹,Weaver James L.¹^ORCID,Howard Kristina E.¹,Chaturbedi Anik¹,Mann John¹,Han Xiaomei¹,Zirkle Joel¹,Arabidarrehdor Ghazal¹²,Rouse Rodney¹,Florian Jeffry¹,Strauss David G.¹^ORCID,Li Zhihua¹^ORCID

Affiliation:

1. Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research US Food and Drug Administration Silver Spring Maryland USA

2. Department of Mechanical Engineering University of Maryland College Park Maryland USA

Funder

Food and Drug Administration

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2686

Reference53 articles.

1. Treatment of SARS with human interferons

2. Update: severe respiratory illness associated with Middle East respiratory syndrome coronavirus (MERS‐CoV)—worldwide, 2012–2013;Gastanaduy P.A.;Morb. Mortal Wkly. Rep.,2013

3. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study

4. COVID-19: Characteristics and Therapeutics

5. COVID-19: Why does disease severity vary among individuals?

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New science, drug regulation, and emergent public health issues: The work of FDA’s division of applied regulatory science;Frontiers in Medicine;2023-01-19