Safety, Tolerability, and Pharmacokinetics of Intravenous Doses of PF‐07304814, a Phosphate Prodrug Protease Inhibitor for the Treatment of SARS‐CoV‐2, in Healthy Adult Participants

Author:

Zhu Tong1,Pawlak Sylvester2,Toussi Sima S.3,Hackman Frances4,Thompson Kimberly2,Song Wei5,Salageanu Joanne6,Winter Erica6,Shi Haihong6,Winton Jennifer6,Binks Michael1

Affiliation:

1. Pfizer Worldwide Research Development and Medical Cambridge Massachusetts USA

2. Pfizer Clinical Research Unit New Haven Connecticut USA

3. Pfizer Worldwide Research Development and Medical, Pearl River New York USA

4. Pfizer Worldwide Research Development and Medical Cambridge UK

5. Pfizer Worldwide Research Development and Medical Groton Connecticut USA

6. Pfizer Global Product Development Groton Connecticut USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference33 articles.

1. COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

2. Johns Hopkins coronavirus resource centre.https://coronavirus.jhu.edu/map.html. Accessed May 18 2021.

3. Comorbidity and its impact on patients with COVID‐19;Sanyaolu A;SN Compr Clin Med,2020

4. Calming the Storm: Natural Immunosuppressants as Adjuvants to Target the Cytokine Storm in COVID-19

5. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

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