CPU0123, a novel endothelin receptor antagonist, relieves hypoxic pulmonary hypertension in rats by suppressing excessive ET-ROS pathway
Author:
Publisher
Wiley
Subject
Drug Discovery
Reference35 articles.
1. Real-time Polymerase Chain Reaction Quantification of Gene Expression Levels of Murine Endothelin-A and Endothelin-B Receptors: Gene Expression Profiles by the Standard Curve Method
2. Pulmonary Hypertension
3. The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx;Acta Pharmacologica Sinica;2012-05
2. Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine;Journal of Biomedical Science;2012-01-08
3. CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation;Naunyn-Schmiedeberg's Archives of Pharmacology;2008-06-12
4. Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats;Journal of Pharmacy and Pharmacology;2008-06
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