Computational and experimental exploration of the structure-activity relationships of flavonoids as potent glyoxalase-I inhibitors-Reference-Cited by-同舟云学术

Computational and experimental exploration of the structure-activity relationships of flavonoids as potent glyoxalase-I inhibitors

Published:2017-12-29 Issue:2 Volume:79 Page:58-69
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Dev. Res.

Author:

Al-Balas Qosay A.¹^ORCID,Hassan Mohammad A.¹,Al-Shar'i Nizar A.¹,El-Elimat Tamam¹,Almaaytah Ammar M.²

Affiliation:

1. Department of Medicinal Chemistry and Pharmacognosy; Jordan University of Science and Technology; Irbid 22110 Jordan

2. Department of Pharmaceutical Technology; Jordan University of Science and Technology; Irbid 22110 Jordan

Funder

Deanship of Academic Research, University of Jordan

Jordan University of Science and Technology

Publisher

Wiley

Subject

Drug Discovery

Reference25 articles.

1. Generation of the first structure-based pharmacophore model containing a selective “zinc binding group” feature to identify potential glyoxalase-1 inhibitors;Al-Balas;Molecules,2012

2. Novel glyoxalase-I inhibitors possessing a “zinc-binding feature” as potential anticancer agents;Al-Balas;Drug Design, Development and Therapy,2016

3. Novel thiazole carboxylic acid derivatives possessing a “zinc binding feature” as potential human glyoxalase-i inhibitors;Al-Balas;Letters in Drug Design & Discovery,2017

4. Crystal structure of human glyoxalase I-evidence for gene duplication and 3D domain swapping;Cameron;The Embo Journal,1997

5. Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue;Cameron;Biochemistry,1999

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