Affiliation:
1. Polymer Research Centre and Centre for Advanced Functional Materials, Department of Chemical Sciences Indian Institute of Science Education and Research Kolkata Nadia West Bengal India
2. Department of Chemical and Pharmaceutical Sciences University of Trieste Trieste Italy
Abstract
AbstractSynthetic anion transporters are potential therapeutics for a plethora of cellular ailments including cystic fibrosis, cancer resistance, epilepsy, etc. In this context, cationic macromolecular amphiphiles are gaining revived interest because of their easy synthesis and ample ion channelization through the membrane barrier. Herein, side chain alanine containing cationic polymer amphiphiles with steroid/fatty acid decoration was established to be an efficient anion‐selective artificial ionophore. The facile amphiphilicity‐assisted assembly makeover of cholic acid containing copolymers channelized the better transmembrane anion transport and efficiency with the maximum selectivity found with NO2− ion.
Subject
Materials Chemistry,Polymers and Plastics,Physical and Theoretical Chemistry