Rational design of hyper‐crosslinked polymers for biomedical applications

Author:

Liao Qian1,Kim Eun Ji2,Tang Yunxin1,Xu Hailang1,Yu Deng‐Guang1,Song Wenliang12ORCID,Kim Bumjoon J.2

Affiliation:

1. School of Materials and Chemistry University of Shanghai for Science and Technology Shanghai China

2. Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon Republic of Korea

Abstract

AbstractHyper‐crosslinked polymers (HCPs) are a family of polymers that possess several desirable characteristics, including high specific surface area, excellent stability, tunable porous structures, and low‐cost reagents. As a result, HCPs have gained significant attention in the areas of gas storage, adsorption, catalysis, separation, and carbon precursors, exhibiting advanced performances in catalytic and energy‐related applications. Recently, researchers have explored the potential of HCPs in biomedical engineering. In this review, we discuss classical synthesis strategies and morphological assembly methods used to create HCPs with unique biological properties. We also highlight the latest advances in emerging biomedical areas of HCPs, such as drug delivery, antimicrobial, bioimaging, and biosensing. By providing various examples, we further discuss the correlations between the structures, morphologies, and enhanced biomedical properties of the HCPs. Finally, we summarize the key applications of HCPs and provide an outlook on the research direction to encourage further development of biomedically available HCPs. Overall, HCPs offer promising potential as a new class of materials for use in biomedical applications, and continued research in this field will lead to exciting discoveries and breakthroughs.

Funder

Korea Institute of Energy Technology Evaluation and Planning

Ministry of Science and Technology of the People's Republic of China

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Physical and Theoretical Chemistry

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