Administration of Fenofibrate Markedly ElevatesFabp3in Rat Liver and Plasma and Confounds Its Use as a Preclinical Biomarker of Cardiac and Muscle Toxicity

Author:

Kochansky Christopher J.12,Lyman Michael J.1,Fauty Scott E.3,Vlasakova Katerina3,D'mello Anil P.2

Affiliation:

1. Pharmacokinetics, Pharmacodynamics and Drug Metabolism; Merck & Co., Inc.; 770 Sumneytown Pike, WP75A-203A, West Point PA 19486 USA

2. Department of Pharmaceutical Sciences; University of the Sciences in Philadelphia; 600 South 43rd Street, Philadelphia PA 19104-4495 USA

3. Safety Assessment; Merck & Co., Inc.; 770 Sumneytown Pike, WP81-217, West Point PA 19486 USA

Publisher

Wiley

Subject

Cell Biology,Organic Chemistry,Biochemistry

Reference72 articles.

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