Activated PPARβ/δ Protects Pancreatic β Cells in Type 2 Diabetic Goto–Kakizaki Rats from Lipoapoptosis via GPR40-Reference-Cited by-同舟云学术

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Activated PPARβ/δ Protects Pancreatic β Cells in Type 2 Diabetic Goto–Kakizaki Rats from Lipoapoptosis via GPR40

Published:2019-07-30 Issue:10 Volume:54 Page:603-616
ISSN:0024-4201
Container-title:Lipids
language:en
Short-container-title:Lipids

Author:

Li Juan¹,Xu Shishi¹,Liu Yuqi¹,Yan Zhe¹,Zhang Fang¹,Lv Qingguo¹,Tong Nanwei¹

Affiliation:

1. Department of Endocrinology and MetabolismWest China Hospital of Sichuan University 37 Guoxuexiang, Chengdu 610041 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Organic Chemistry,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/lipd.12182

Reference30 articles.

1. Insulin Sensitivity Indices Calculated from Basal and OGTT-Induced Insulin, Glucose, and FFA Levels

2. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.

3. Palmitate and insulin synergistically induce IL-6 expression in human monocytes

4. Activation of PPARδ up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate

5. PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation

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1. Homotherapy for heteropathy: Interleukin‐41 and its biological functions;Immunology;2024-04-09

2. Indirect comparison of efficacy and safety of chiglitazar and thiazolidinedione in patients with type 2 diabetes: A meta-analysis;World Journal of Diabetes;2023-10-15

3. PPARβ down-regulation is involved in high glucose-induced endothelial injury via acceleration of nitrative stress;Microvascular Research;2022-01

4. Molecular Mechanisms of Apoptosis Induction and Its Regulation by Fatty Acids in Pancreatic β-Cells;International Journal of Molecular Sciences;2021-04-20

5. Meteorin-like protein (METRNL)/IL-41 improves LPS-induced inflammatory responses via AMPK or PPARδ–mediated signaling pathways;Advances in Medical Sciences;2021-03

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