Eco‐friendly materials for next‐generation vaccination: From concept to clinical reality

Author:

Kaushik Neha1,Patel Paritosh2,Gupta Ravi3ORCID,Jaiswal Apurva2,Negi Manorma2,Borkar Shweta Bharat2,Mishra Yogendra Kumar4ORCID,Kim June Hyun1,Choi Eun Ha2,Kaushik Nagendra Kumar2ORCID

Affiliation:

1. Department of Biotechnology The University of Suwon Hwaseong Korea

2. Department of Electrical and Biological Physics, Plasma Bioscience Research Center Kwangwoon University Seoul Korea

3. College of General Education Kookmin University Seoul Korea

4. Mads Clausen Institute, NanoSYD University of Southern Denmark Alsion Sønderborg Denmark

Abstract

AbstractThe vaccine is a premier healthcare intervention strategy in the battle against infectious infections. However, the development and production of vaccines present challenges in terms of complexity, cost, and time consumption. Alternative methodologies, such as nonthermal plasma and plant‐based technologies, have emerged as potential alternatives for conventional vaccine manufacturing processes. While plasma‐based approaches offer a rapid and efficient pathogen inactivation method devoid of harsh reagents, plant‐based techniques present a more economically viable and scalable avenue for vaccine production. The imperative urges these approaches to address pressing global health challenges posed by emerging and recurring infectious diseases, surpassing the limitations of traditional vaccine fabrication methods. The primary goal of this review is to provide a comprehensive overview of the current research landscape, covering conceptualization, production, and potential advantages of plasma‐based and plant‐based vaccines. Furthermore, exploring the obstacles and opportunities intrinsic to these strategies is undertaken, elucidating their potential impact on vaccination strategies. This systematic presentation specifies a detailed outline of recent vaccine research and developments, emphasizing the possibility of advanced green approaches to produce effective and secure vaccination programs.

Funder

National Research Foundation of Korea

Publisher

Wiley

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