Affiliation:
1. State Key Laboratory of Chemical Engineering, School of Chemical Engineering East China University of Science and Technology Shanghai People's Republic of China
Abstract
AbstractBACKGROUNDPyraclostrobin manifests a bright promise in agriculture with the characteristics of a broad spectrum, high efficiency, low toxicity, non‐target biosafety, and friendliness to users and the environment due to its ability to inhibit mitochondrial respiration in a novel mode of action. 1‐(4‐chlorophenyl)‐3‐pyrazolol is an essential intermediate for the preparation of pyraclostrobin. The commercial technology for the production of 1‐(4‐chlorophenyl)‐3‐pyrazolol by oxidizing 1‐(4‐chlorophenyl)pyrazolidan‐3‐one with H2O2 in strong an alkali solution is risky and not friendly to the environment.RESULTSA solid Fe/AC catalyst is constructed by loading ferric on commercial activated carbon. The activated carbon and ferric act cooperatively to upgrade the oxidation rate of 1‐(4‐chlorophenyl)pyrazolidan‐3‐one and the yield of 1‐(4‐chlorophenyl)‐3‐pyrazolol with air. The best catalyst is Fe/AC supported with 15% Fe2O3 on activated carbon of 100 ~ 120 mesh without activation.CONCLUSIONThe Fe/AC catalyst is able to not only accelerate the oxidation of 1‐(4‐chlorophenyl) pyrazolidin‐3‐one but also obtain a higher yield of 1‐(4‐chlorophenyl)‐3‐pyrazolol than FeCl3 or activated carbon can in 5%(wt.) NaOH solution. The highest 1‐(4‐chlorophenyl)‐3‐pyrazolol yield is obtained by a gas stream containing 60%(wt.) oxygen with a Fe/AC dosage of 1.25 g L−1. © 2023 Society of Chemical Industry.
Subject
Inorganic Chemistry,Organic Chemistry,Pollution,Waste Management and Disposal,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Biotechnology