1. Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, School of Life Sciences, Fudan University Shanghai People's Republic of China
2. These authors should be considered co–first authors
3. Tumor Virus RNA Biology Section, Gene Regulation and Chromosome Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health Frederick Maryland
4. Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda Maryland
5. Corresponding author