Blocking CCN2 Reduces Progression of Sensorimotor Declines and Fibrosis in a Rat Model of Chronic Repetitive Overuse-Reference-Cited by-同舟云学术

Blocking CCN2 Reduces Progression of Sensorimotor Declines and Fibrosis in a Rat Model of Chronic Repetitive Overuse

Published:2019-06-20 Issue:9 Volume:37 Page:2004-2018
ISSN:0736-0266
Container-title:Journal of Orthopaedic Research
language:en
Short-container-title:J. Orthop. Res.

Author:

Barbe Mary F.¹^ORCID,Hilliard Brendan A.¹,Delany Sean P.¹,Iannarone Victoria J.¹,Harris Michele Y.¹,Amin Mamta¹,Cruz Geneva E.¹,Barreto‐Cruz Yeidaliz¹,Tran Ngih¹, Day Emily P.¹,Hobson Lucas J.¹,Assari Soroush²,Popoff Steven N.¹

Affiliation:

1. Department of Anatomy and Cell Biology, Lewis Katz School of MedicineTemple University Philadelphia Pennsylvania 19140

2. Department of Mechanical Engineering, College of EngineeringTemple University Philadelphia Pennsylvania 19122

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

Wiley

Subject

Orthopedics and Sports Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jor.24337

Reference50 articles.

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4. Connective tissue growth factor (CCN2) is a matricellular preproprotein controlled by proteolytic activation

5. CCN3 (NOV) Is a Negative Regulator of CCN2 (CTGF) and a Novel Endogenous Inhibitor of the Fibrotic Pathway in an in Vitro Model of Renal Disease

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