Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models-Reference-Cited by-同舟云学术

Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models

Published:2016-07 Issue: Volume:56 Page:S99-S109
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Varma Manthena V.¹,El-Kattan Ayman F.²

Affiliation:

1. Pharmacokinetics; Dynamics and Metabolism; Worldwide Research and Development; Pfizer Inc; Groton CT USA

2. Pharmacokinetics; Dynamics and Metabolism; Worldwide Research and Development; Pfizer Inc; Cambridge MA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference94 articles.

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5. Predicting clearance mechanism in drug discovery: extended clearance classification system (ECCS);Varma;Pharm Res,2015

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