Sarcopenia and noncoding RNAs: A comprehensive review-Reference-Cited by-同舟云学术

Sarcopenia and noncoding RNAs: A comprehensive review

Published:2023-05-14 Issue:7 Volume:238 Page:1416-1430
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:Journal Cellular Physiology

Author:

Ghafouri‐Fard Soudeh¹^ORCID,Askari Arian²,Mahmud Hussen Bashdar³,Taheri Mohammad⁴^ORCID,Kiani Arda⁵

Affiliation:

1. Department of Medical Genetics, School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran

2. Phytochemistry Research Center Shahid Beheshti University of Medical Sciences Tehran Iran

3. Department of Clinical Analysis, College of Pharmacy Hawler Medical University Kurdistan Region Iraq

4. Institute of Human Genetics Jena University Hospital Jena Germany

5. Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran Iran

Abstract

AbstractSarcopenia is an elderly disease and is related to frailty and loss of muscle mass (atrophy) of older adults. The exact molecular mechanisms contributing to the pathogenesis of disease are yet to be discovered. In recent years, the role of noncoding RNAs in the pathogenesis of almost every kind of malignant and nonmalignant conditions is pinpointed. Regarding their regulatory function, there have been an increased number of studies on the role of noncoding RNAs in the progress of sarcopenia. In this manuscript, we review the role of microRNAs and long noncoding RNAs in development and progression of disease. We also discuss their potential as therapeutic targets in this condition.

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.31031

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