Bornyl acetate has an anti-inflammatory effect in human chondrocytes via induction of IL-11

Author:

Yang He1,Zhao Rugang1,Chen Hao1,Jia Pu1,Bao Li1,Tang Hai1

Affiliation:

1. Department of Orthopedic Surgery; Beijing Friendship Hospital, Capital Medical University; Beijing People's Republic of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Genetics,Molecular Biology,Biochemistry

Reference20 articles.

1. The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes;Elliott;Arthritis Res Ther,2003

2. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage;Mitchell;J. Clin. Invest,1996

3. Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases;Maier;J. Biol. Chem,1993

4. Important immunoregulatory role of interleukin-11 in the inflammatory process in rheumatoid arthritis;Hermann;Arthritis Rheum,1998

5. Stimulation of Rho signaling by pathologic mechanical stretch is a “second hit” to rho-independent lung injury induced by IL-6;Birukova;Am. J. Physiol. Lung Cell Mol. Physiol,2012

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