The 14C, 13C, and 15N syntheses of a potent VEGFR-2 kinase inhibitor, Brivanib, and its prodrug, Brivanib Alaninate-Reference-Cited by-同舟云学术

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The 14C, 13C, and 15N syntheses of a potent VEGFR-2 kinase inhibitor, Brivanib, and its prodrug, Brivanib Alaninate

Published:2011-02-17 Issue:6 Volume:54 Page:324-331
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Tran Scott B.,Lago Michael W.,Tian Yuan,Gong Sharon X.,Batra Indu,Allentoff Alban J.,Maxwell Brad D.,Bonacorsi Samuel J.,Ogan Marc,Rinehart J. Kent,Balasubramanian Balu

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.1871/fullpdf

Reference11 articles.

1. VEGF and the quest for tumour angiogenesis factors

2. VEGF/VEGFR signalling as a target for inhibiting angiogenesis

3. Discovery and Preclinical Studies of (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an In Vivo Active Potent VEGFR-2 Inhibitor

4. A Simple Synthesis of Pyrroles

5. Synthesis of 1-(1,1-dimethylethyl)-1H-pyrazole-4-carboxylate ester derivatives

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