Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human <scp>UGT2</scp> enzymes-Reference-Cited by-同舟云学术

Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes

Published:2022-11-24 Issue:6 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Kobayashi Kaoru¹^ORCID,Deguchi Tsuneo²,Abe Satoshi³^ORCID,Kajitani Naoyo³,Kazuki Kanako³,Takehara Shoko³,Nakamura Kazuomi⁴,Kurihara Atsushi²,Oshimura Mitsuo³,Kazuki Yasuhiro³⁵

Affiliation:

1. Department of Biopharmaceutics, Graduate School of Clinical Pharmacy Meiji Pharmaceutical University Kiyose, Tokyo Japan

2. Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd. Chuo‐ku, Tokyo Japan

3. Chromosome Engineering Research Center (CERC) Tottori University Yonago, Tottori Japan

4. Advanced Medicine, Innovation and Clinical Research Center Tottori University Hospital Yonago, Tottori Japan

5. Department of Chromosome Biomedical Engineering, School of Life Science, Faculty of Medicine Tottori University Yonagi, Tottori Japan

Funder

Core Research for Evolutional Science and Technology

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.1030

Reference35 articles.

1. The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms

2. Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

3. The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification

4. Human UDP-Glucuronosyltransferase 2B7

5. Human UGT2B7 catalyzes morphine glucuronidation;Coffman BL;Drug Metab Dispos,1997

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