Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency

Author:

Stindt Jan1,Kluge Stefanie1,Dröge Carola1,Keitel Verena1,Stross Claudia1,Baumann Ulrich2,Brinkert Florian3,Dhawan Anil4,Engelmann Guido56,Ganschow Rainer37,Gerner Patrick89,Grabhorn Enke3,Knisely A. S.10,Noli Khalid A.11,Pukite Ieva12,Shepherd Ross W.13,Ueno Takehisa14,Schmitt Lutz15,Wiek Constanze16,Hanenberg Helmut16,Häussinger Dieter1,Kubitz Ralf117

Affiliation:

1. Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty; Heinrich Heine University; Düsseldorf Germany

2. Pediatric Gastroenterology and Hepatology, Department for Pediatric Kidney, Liver and Metabolic Diseases; Hannover Medical School; Hannover Germany

3. Pediatric Hepatology and Liver Transplantation, Transplantation Center; University Medical Center Hamburg-Eppendorf; Hamburg Germany

4. Pediatric Liver Center; King's College Hospital; London United Kingdom

5. Department of General Pediatrics; Heidelberg University Hospital; Heidelberg Germany

6. Pediatric Clinic; Lukaskrankenhaus GmbH; Neuss Germany

7. Clinic of General Pediatrics; University Hospital; Bonn Germany

8. Department for Pediatric Nephrology, Gastroenterology, Endocrinology and Transplant Medicine, Clinic for Pediatrics II, University Children's Hospital Essen; University Duisburg-Essen; Essen Germany

9. Children's Hospital; Albert Ludwigs University; Freiburg Germany

10. Institute of Liver Studies; King's College Hospital; London United Kingdom

11. Clinical Laboratory Services Division; Dhahran Health Center; Dhahran Saudi Arabia

12. Latvian Center of Pediatric Gastroenterology/Hepatology; University Children's Hospital; Riga Latvia

13. Texas Children's Hospital Liver Center, Baylor College of Medicine, Gastroenterology; Houston TX

14. Pediatric Surgery/Pediatric Liver and GI Transplant; Osaka University Graduate School of Medicine; Osaka Japan

15. Institute of Biochemistry; Heinrich Heine University; Düsseldorf Germany

16. Department of Otorhinolaryngology (ENT); Heinrich Heine University School of Medicine; Düsseldorf Germany

17. Medical Clinic I; Bethanien Hospital; Moers Germany

Funder

Clinical Research Group KFO217 “Hepatobiliary transport and liver diseases”

Collaborative Research Center 974 “Communication and System Relevance in Liver Damage and Regeneration”

Research Commission of the Medical Faculty

Strategic Research Commission of the Heinrich Heine University

Publisher

Wiley

Subject

Hepatology

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