Non-invasivein vivoimaging of early metabolic tumor response to therapies targeting choline metabolism

Author:

Mignion Lionel1,Danhier Pierre1,Magat Julie1,Porporato Paolo E.2,Masquelier Julien3,Gregoire Vincent4,Muccioli Giulio G.3,Sonveaux Pierre2,Gallez Bernard1,Jordan Bénédicte F.1

Affiliation:

1. Biomedical Magnetic Resonance Group; Louvain Drug Research Institute, Université Catholique De Louvain (UCL); Avenue Mounier, 73 Box B1.73.08 Brussels Belgium

2. Pole of Pharmacology, Institut De Recherche Expérimentale Et Clinique (IREC); Université Catholique De Louvain (UCL); Avenue Mounier, 52 Box B1.53.09 Brussels Belgium

3. Bioanalysis and Pharmacology of Bioactive Lipids Research Group, Louvain Drug Research Institute, Université Catholique De Louvain (UCL); Avenue Mounier, 72 Box B1.72.01 Brussels Belgium

4. Center for Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique (IREC); Université catholique de Louvain (UCL); Avenue Hippocrate, 55 Box B1.55.02 Brussels Belgium

Funder

Belgian National Fund for Scientific Research

European Research Council

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference27 articles.

1. Choline metabolism in malignant transformation;Glunde;Nat Rev Cancer,2011

2. Therapeutic targets and biomarkers identified in cancer choline phospholipid metabolism;Glunde;Pharmacogenomics,2006

3. Choline phosphokinase;Wittenberg;J Biol Chem,1953

4. Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells;Aboagye;Cancer Res,1999

5. Structure and function of choline kinase isoforms in mammalian cells;Aoyama;Prog Lipid Res,2004

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