Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator

Author:

Muehlan Clemens1,Brooks Sander23,Vaillant Cedric4,Meinel Michael5,Jacobs Gabriël E.26,Zuiker Rob G.2,Dingemanse Jasper1

Affiliation:

1. Department of Clinical Pharmacology Idorsia Pharmaceuticals Ltd. Allschwil Switzerland

2. Centre for Human Drug Research Leiden The Netherlands

3. Department of Anesthesiology Erasmus University Medical Center Rotterdam The Netherlands

4. Global Life Cycle Management Idorsia Pharmaceuticals Ltd. Allschwil Switzerland

5. Department of Biometry Idorsia Pharmaceuticals Ltd. Allschwil Switzerland

6. Department of Psychiatry Leiden University Medical Center Leiden The Netherlands

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference39 articles.

1. European Commission Directorate General for Transport.Annual accident report (2018). Accessed May 12 2021.

2. U.S. Department of Transportation.Traffic safety facts 2017. A compilation of motor vehicle crash data (2017). Accessed May 12 2021.

3. The Efficacy and Safety of Drug Treatments for Chronic Insomnia in Adults: A Meta-analysis of RCTs

4. Lorazepam impairs highway driving performance more than heavy alcohol consumption

5. Comparing the effects of oxazepam and diazepam in actual highway driving and neurocognitive test performance: a validation study

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