Implementation of an experimental and computational tool set to study protein‐mAb interactions
Author:
Affiliation:
1. Department of Chemical and Biological EngineeringRensselaer Polytechnic Institute Troy New York
2. Purification Process SciencesMedImmune LLC Gaithersburg Maryland
Funder
MedImmune
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.2825
Reference66 articles.
1. A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies
2. Identification of an IgG CDR sequence contributing to co-purification of the host cell protease cathepsin D
3. Trace levels of the CHO host cell protease cathepsin D caused particle formation in a monoclonal antibody product
4. Development of robust antibody purification by optimizing protein-A chromatography in combination with precipitation methodologies
5. Analysis of host-cell proteins in biotherapeutic proteins by comprehensive online two-dimensional liquid chromatography/mass spectrometry
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