Treg cell therapy: How cell heterogeneity can make the difference

Author:

Giganti Giulio1,Atif Muhammad2ORCID,Mohseni Yasmin1,Mastronicola Daniela1ORCID,Grageda Nathali1,Povoleri Giovanni AM3ORCID,Miyara Makoto2,Scottà Cristiano1ORCID

Affiliation:

1. “Peter Gorer” Department of Immunobiology, School of Immunology & Microbiological Sciences King's College London London UK

2. Sorbonne Université, Inserm, Centre d'immunologie et des maladies infectieuses, Paris (CIMI‐PARIS) AP‐HP Hôpital Pitié‐Salpêtrière Paris France

3. Centre for Inflammation Biology and Cancer Immunology, Department of Inflammation Biology, School of Immunology & Microbial Sciences King's College London London UK

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference130 articles.

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2. Immunologic self‐tolerance maintained by activated T cells expressing IL‐2 receptor alpha‐chains (CD25). Breakdown of a single mechanism of self‐tolerance causes various autoimmune diseases;Sakaguchi S.;J. Immunol.,1995

3. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

4. The lifestyle of naturally occurring CD4+CD25+Foxp3+ regulatory T cells

5. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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