MicroRNA-320a and microRNA-4496 attenuateHelicobacter pyloricytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting β-catenin and ATP-binding cassette, subfamily G, member 2

Author:

Kang Dong Woo12,Yang Eun Sun1,Noh Yu Na1,Hwang Won Chan1,Jo Se-Young2,Suh Young-Ah2,Park Won Sang3,Choi Kang-Yell45,Min Do Sik15

Affiliation:

1. Department of Molecular Biology, College of Natural Science; Pusan National University; Busan Republic of Korea

2. Institute of Innovative Cancer Research, Asan Institute for Life Science, Asan Medical Centre; University of Ulsan College of Medicine; Seoul Republic of Korea

3. Department of Pathology, College of Medicine; The Catholic University of Korea; Seoul Republic of Korea

4. Department of Biotechnology, College of Life Science and Biotechnology; Yonsei University; Seoul Republic of Korea

5. Translational Research Centre for Protein Function Control; Yonsei University; Seoul Republic of Korea

Funder

National Research Foundation of Korea

Translational Research Centre for Protein Function Control

National R&D Program for Cancer Control (Ministry for Health, Welfare, and Family Affairs)

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference54 articles.

1. Parasitism by the ‘slow’ bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia;Blaser;J Clin Invest,1994

2. Is gastric carcinoma an infectious disease?;Correa;N Engl J Med,1991

3. Helicobacter pylori and gastric cancer: factors that modulate disease risk;Wroblewski;Clin Microbiol Rev,2010

4. Oncogenic mechanisms of the Helicobacter pylori CagA protein;Hatakeyama;Nat Rev Cancer,2004

5. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach;Blaser;Cancer Res,1995

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