Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario

Author:

Ghorbani Hamidreza1ORCID,Emadi Torghabeh Ali2ORCID,Farzadnia Mahdi3ORCID,Golshan Alireza1ORCID,Rabiei Parisa2ORCID

Affiliation:

1. Kidney Transplantation Complications Research Center Mashhad University of Medical Sciences Mashhad Iran

2. Cancer Research Center Mashhad University of Medical Sciences Mashhad Iran

3. Department of Pathology Mashhad University of Medical Sciences Mashhad Iran

Abstract

AbstractBackgroundRenal metastasis is a rare manifestation of germ cell tumors. Extension of malignant lesions into the renal vein can complicate the scenario.CaseThis report presents a 35‐year‐old man with primary stage IS NSGCT. Fourteen months after radical orchiectomy he presented with metastasis in the lung, kidney, and para‐aortic lymph nodes. He received multiple lines of salvage treatments including chemotherapy and surgery. Intraoperative exploration during radical nephrectomy and retroperitoneal lymphadenectomy revealed intra‐renal vein involvement with a prominent teratomatous component.ConclusionDefining the exact extent of malignant lesions, especially endovascular lesions, is very important to clarify how advanced the malignant lesions are. The surgeons must be aware of the risk factors that predict vascular involvement, and therefore, providing intraoperative access to vascular surgery procedures when needed.

Publisher

Wiley

Subject

Cancer Research,Oncology

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