Biventricular catheterization combined with pressure‐volume loop monitoring provides insight into the dynamic effects of left ventricular assist devices ramp on right ventricular function

Author:

Garmany Armin1ORCID,Inglis Sara S.23,Behfar Atta234,Rosenbaum Andrew N.23ORCID

Affiliation:

1. Graduate School of Biomedical Sciences, Alix School of Medicine, Medical Scientist Training Program, Mayo Clinic Rochester Minnesota USA

2. Department of Cardiovascular Medicine, Division of Circulatory Failure Mayo Clinic Rochester Minnesota USA

3. VanCleve Cardiac Regenerative Medicine Program and Fong Chao Foundation, Center for Regenerative Medicine, Mayo Clinic Rochester Minnesota USA

4. William J von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic Rochester Minnesota USA

Abstract

AbstractRamp studies are utilized for speed optimization of continuous flow left ventricular assist devices (CF‐LVADs). We here report the utility of combined left and right heart catheterization during a ramp study to ensure a comprehensive understanding of the hemodynamic implications on both ventricles. Pressure‐volume loop (PV loop) monitoring uncovered compromised systolic and mildly compromised right ventricular function with increasing LVAD speeds, despite improvement in left ventricular unloading. These findings informed patient management and highlight the potential utility of PV loop monitoring as an adjunct to left and right heart catheterization during ramp studies of next‐generation LVADs.

Publisher

Wiley

Reference9 articles.

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5. Development of a Novel Echocardiography Ramp Test for Speed Optimization and Diagnosis of Device Thrombosis in Continuous-Flow Left Ventricular Assist Devices

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