An innovative strategy to recycle permeate in biologics continuous manufacturing process to improve material efficiency and sustainability
Author:
Affiliation:
1. Biologics Upstream Process Development Merck & Co., Inc. Kenilworth New Jersey USA
2. Biologics Downstream Process Development Merck & Co., Inc. Kenilworth New Jersey USA
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3262
Reference22 articles.
1. Principles and approach to developing mammalian cell culture media for high cell density perfusion process leveraging established fed-batch media
2. The design basis for the integrated and continuous biomanufacturing framework
3. The business impact of an integrated continuous biomanufacturing platform for recombinant protein production
4. A straightforward methodology for designing continuous monoclonal antibody capture multi-column chromatography processes
5. Effective Antibody Production by Reusing Culture Medium Previously Used in Antibody Purification
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1. Process intensification in biopharmaceutical process development and production – an industrial perspective;Physical Sciences Reviews;2023-11-13
2. Continuous Bioprocessing for Upstream Process: Perfusion Process;Cell Engineering;2023
3. Comparison of process mass intensity (PMI) of continuous and batch manufacturing processes for biologics;New Biotechnology;2022-12
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