Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether and their major metabolites dihydroartemisinin and dihydroartemisinin-glucuronide in sheep plasma

Author:

Duthaler Urs,Keiser Jennifer,Huwyler Jörg

Publisher

Wiley

Subject

Spectroscopy

Reference34 articles.

1. Qinghaosu (artemisinin): the price of success;White;Science,2008

2. Management of severe and complicated malaria;Mishra;J. Postgrad. Med.,2006

3. The rat biliary metabolites of dihydroartemisinin, an antimalarial endoperoxide;Maggs;Drug Metab. Dispos.,1997

4. Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether;Ramu;J. Med. Chem.,1995

5. Artesunate and artemether are effective fasciolicides in the rat model and in vitro;Keiser;J. Antimicrob. Chemother.,2006

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