Metabolic profiles of 20(S )-protopanaxadiol in rats after oral administration using ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry-Reference-Cited by-同舟云学术

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Metabolic profiles of 20(S )-protopanaxadiol in rats after oral administration using ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry

Published:2014-02-07 Issue:6 Volume:28 Page:595-604
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

He Chunyong¹²,Li Jia¹²,Wang Rufeng¹²,Li Zeyun¹³,Annie Bligh S. W.⁴,Yang Li¹³,Wang Zhengtao¹³²

Affiliation:

1. The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines; Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine; Shanghai 201203 China

2. Department of Pharmacognosy; China Pharmaceutical University; Nanjing 210038 China

3. Shanghai R&D Centre for Standardization of Chinese Medicines; Shanghai 201203 China

4. Department of Complementary Medicine, Faculty of Science and Technology; University of Westminster; 115 New Cavendish Street London W1W 6UW UK

Funder

National Natural Science Foundation of China

Program for Changjiang Scholars and Innovative Research Team in University

China Postdoctoral Science Foundation

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/rcm.6813/fullpdf

Reference25 articles.

1. Biotransformation of ginsenoside Rd in the ginseng extraction residue by fermentation with lingzhi (Ganoderma lucidum);Hsu;Food Chem.,2013

2. Potential role of ginseng in the treatment of colorectal cancer;Wang;Am. J. Chin. Med.,2008

3. Isolation and analysis of ginseng: advances and challenges;Qi;Nat. Prod. Rep.,2011

4. American ginseng: Potential structure-function relationship in cancer chemoprevention;Qi;Biochem. Pharmacol.,2010

5. Detection of adulteration of notoginseng root extract with other Panax species by quantitative HPLC coupled with PCA;Wang;J. Agric. Food Chem.,2009

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1. Comparative Characterization of the Ginsenosides from Six Panax Herbal Extracts and Their In Vitro Rat Gut Microbial Metabolites by Advanced Liquid Chromatography–Mass Spectrometry Approaches;Journal of Agricultural and Food Chemistry;2023-06-09

2. A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats;Journal of Pharmaceutical and Biomedical Analysis;2021-05

3. Characterization of the metabolites of GW1929 in rat by liquid chromatography coupled with electrospray ionization tandem mass spectrometry;Rapid Communications in Mass Spectrometry;2020-01-09

4. Tentative identification of 20(S)-protopanaxadiol metabolites in human plasma and urine using ultra-performance liquid chromatography coupled with triple quadrupole time-of-flight mass spectrometry;Journal of Ginseng Research;2019-10

5. Dose‐dependent exposure profile and metabolic characterization of notoginsenoside R1in rat plasma by ultra‐fast liquid chromatography–electrospray ionization–tandem mass spectrometry;Biomedical Chromatography;2019-08-28

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