MULTISCALE MODELING OF A PHARMACEUTICAL FLUID BED COATING PROCESS USING CFD/DEM AND POPULATION BALANCE MODELS TO PREDICT COATING UNIFORMITY

Author:

Sarkar Avik1,Shoemaker Brian1,Doshi Pankaj1,am Ende Mary T.1,Jajcevic Dalibor2,Böhling Peter2,Toson Peter2,Zadravec Matej2,Khinast Johannes G.23

Affiliation:

1. Process Modeling & Engineering Technology Group; Pfizer Inc.; Groton CT USA

2. Research Center Pharmaceutical Engineering GmbH; Graz Austria

3. Institute for Process and Particle Engineering Graz University of Technology; Graz Austria

Publisher

John Wiley & Sons, Inc.

Reference60 articles.

1. Large-scale CFD-DEM simulations of fluidized granular systems;Jajcevic;Chem Eng Sci,2013

2. Numerical study of segregation using a new drag force correlation for polydisperse systems derived from lattice-Boltzmann simulations;Beetstra;Chem Eng Sci,2007

3. The voidage function for fluid: particle interaction systems;Felice;Int J Multiph Flow,1994

4. Computer simulation of bubbles in a fluidized bed;Syamlal;AIChE Symp. Ser.,1989

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